Amyloid beta peptide (Aβ) is produced through the proteolytic processing of a transmembrane protein, amyloid precursor protein (APP), by β- and γ-secretases. Aβ accumulation in the brain is proposed ...
There’s an age-old adage in biology: structure determines function. To understand the function of the myriad proteins that perform vital jobs in a healthy body—or malfunction in a diseased ...